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Table 1 Genes associated with variation in taste and olfactory ability in humans

From: Heritable differences in chemosensory ability among humans

Gene Polymorphisms Taste/odor Reference/s
TAS2R38 P49A, A262V, V296I Phenylthiocarbamide (PTC) [13, 14]
TAS2R31 C103T, R35W Saccharin, acesulfame K [11, 15]
TAS2R19 R299Ca Quinine [14]
TAS1R3 Promoter SNPs at −1266 and 1572 Sucrose [16]
GNAT3 Promoter SNP at -10127a Sucrose [17]
TAS1R1 T372A, R757C Monosodium glutamate [18]
OR7D4 R88W, T133M Androstenone [19, 20]
OR11H7P Q227cb Isovaleric acid [21]
OR2J3 T113A, R226Q Cis-3-hexen-1-ol [22, 23]
OR2M7 c ND Metabolites of asparagus [24, 25]
  1. ND, not determined.
  2. aBest associated single-nucleotide polymorphism (SNP) but not necessarily causal.
  3. bNonsense mutation.
  4. cClosest olfactory receptor gene.